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Levothyroxine, also L-thyroxine or T4, is a artificial form of the thyroid hormone thyroxine, which is normally secreted near thefollicular cells of the thyroid gland. It is also employed to go into thyroid hormone deficiency, and then to foil the recurrence of thyroid cancer. Like its consequently secreted counterpart, levothyroxine is chemically in the chiral L-form. The correlated cure dextrothyroxine (D-thyroxine) was employed in the times gone by as a treatment as a replacement for hypercholesterolemia (happy cholesterol levels) but was aloof apposite to cardiac side-effects.
Experience
Thyroxine was anything else individual in unalloyed form in 1914 at the Mayo Clinic around Edward Calvin Kendall from extracts of hog thyroid glands.[3 - The hormone was synthesised in 1927 by way of British chemists Charles Robert Harington and George Barger.
Medical uses
Levothyroxine is typically adapted to to treat hypothyroidism.[4 - It may also be utilized to treat goiter via its faculty to downgrade thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.[5 - [6 - In 1992, President George H.W. Bush told television pack Larry King that he had been prescribed levothyroxine as corner of a treatment regimen in behalf of Graves\' contagion; the interchange was disseminate contemporary to follower dish owners tracking and recording backhaul channels.[7 -
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